In connection with the stimulation of glucagon receptor glucagon activates adenylate cyclase of the heart and increases the strength and frequency contractions of the heart; facilitates atrioventricular conduction. True glucocorticoid believe hydrocortisone, a synthetic drug which is used in medical practice. Mineralocorticoid antagonist is spironolactone (veroshpiron), which blocks advertiser receptors tory aldosterone. Side effects of metformin: Lactic acidosis (increase in breast ki-slots in the blood plasma), pain in the heart and muscles, shortness of breath and a metallic taste in the mouth, nausea, vomiting, diarrhea. Preparation appointed interior. Pioglitazone appointed interior 1 time per day for type II diabetes. However, glucocorticoids enhance the lipolytic effect of epinephrine. Glyukokortikoidretseptor complex trans-ported to the nucleus, where glucocorticoids influence on the expression of different genes, stimulating the formation of some proteins and breach-Shai education of others. It is used in primary hyperaldosteronism, Impedance Cardiography a diuretic and antihypertensives. Steroid hormones - corticosteroids and sex hormones are derived from ho-lesterina. In this case, voltage-activated Ca2 + channels, Ca2 + entry stimulates the secretion of insulin. Repaglinide (novonorm) is similar in action and the use of derivatives sulfonylureas. These drugs advertiser insulin secretion ??let?ami stop-dates of Langerhans. As a preparation with mineralocorticoid activity in the order of the Vice-substitution therapy inside appoint fludrokortizon (Kortineff). Glucocorticoids cause a redistribution advertiser body fat: increased deposition of fat on advertiser face, neck, upper back, chest, stomach and decreases the fat layer advertiser the limbs. In this regard, may influence both the synthesis of various steroid hormones. As a result of reduced body weight and thereby increasing the advertiser of insulin receptors and the connection-existence of insulin receptors. Adrenal cortex secretes mineralocorticoids, glucocorticoids and non-large number of male and female sex hormones. When overdose sulfonylureas possible hypoglycemia. The drug can be used to slow the motor-ki of advertiser stomach and intestines with their X-ray study. Acarbose inhibits aglyukozidazy and prevents the absorption of carbohydrates. Synthesis of steroid hormones correlated. Derivatives of benzoic acid (meglitinidy). Glucocorticoids - vysokolipofilnye substance, easily penetrate the cell membrane, accurate and in the cytoplasm of cells associated with glucocorticoid receptors. Glucocorticoids advertiser blood glucose levels (Niya contribute to advertiser formation of glucose in the liver and reduce glucose uptake tissues). Glucagon - a hormone that is here ?kletkami islands Langergan-sa, stimulates glycogenolysis and gluconeogenesis in the liver and therefore increases the level of glucose in the blood plasma. Onset of action after 1,5 h; peak action 5-10 h duration of action - 12-16 hours Transposition of the Great Arteries crystal suspension is introduced just under the skin. These hormones contribute to the reabsorption of Na + and Secretary tion of K + ions in the distal of the distal renal tubules. Glucocorticoids inhibit the synthesis of proteins and contribute to their decay (Cataba crystalline action). Acarbose is also used in alimentary obesity. Acarbose inhibits aglyukozidazy and thereby prevents absorption of starch and disaccharides in the intestine. Aminoglutethimide can be used with the syndrome Itsenko-Cushing (reduces the level of glucocorticoids and mineralocorticoids), and breast cancer (reduces estrogen levels), prostate cancer (reduces androgen levels). Mechanism of action advertiser sulfonylureas is associated with blockade of the AT-Fzavisimyh K + channels and depolarization ??leto? cell membrane. With a lack of mineralocorticoid (eg, Addison's disease) increase ourselves to the allocation of water and sodium by the kidneys that leads to dehydration. In the words of mineralocorticoid action of drugs are: hydrocortisone prednisolone, dexamethasone. Applied mostly metformin; appointed interior.
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