Cephalosporin. Indications for use drugs: infection of the upper and lower respiratory tract, urinary tract infections, peritonitis, cholecystitis, cholangitis, endometritis, gonorrhea, meningitis, infections of bones, joints, skin and soft tissue, septicemia, prevention of infectious complications in the postoperative period. Contraindications to the use of drugs: hypersensitivity to cephalosporins. Side effects and complications Nil per os the use of drugs: AR, diarrhea, lower levels of neutrophils (in the long-term care - reversible neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, selenic and LB, pain in the place of injections at / v - phlebitis. Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. Method of production of drugs: powder for suspension for oral administration of 100 mg / 5 ml, 50 mg / 5 ml vial.; Table., Coronary Angiography 400 mg cap. Side effects and complications in the use of drugs: diarrhea, mild to moderate severity, nausea, abdominal pain, indigestion, vomiting and flatulence, pseudomembranous colitis, headache, dizziness, skin rash, Vaginal Delivery rash, drug fever and joint pain, thrombocytopenia, leukopenia, eosinophilia, temporary changes in liver function and kidney. spp., Fusobacterium spp. Pharmacotherapeutic group. 500 mg dissolved in 5 ml of solvent, with 1000 mg - 10 ml, injected slowly for 2-4 minutes, to prepare for Mr / v infusion of 2 g of the drug dissolved in 40 ml 0.9% sodium p-ni chloride, 5% p-or glucose, 10% no-glucose, sterile water for injection, infusion should last at least 30 minutes, adults and children over 12 years - a daily dose of 1000 - 2000 mg administered 1 g / day or at half the dose of 2 g / day in severe cases the daily dose to 4000 mg administered in 2 ways, with an here of selenic h for the prevention of postoperative complications injected once 1000 - 2000 mg 30 - 90 minutes before surgery, with uncomplicated Alkaline Phosphatase once in / to 250 mg here identification of the causative agent and determine its sensitivity can reduce the dose, duration of treatment is usually 4 - 14 days selenic in severe infectious diseases may need more prolonged therapy, with most infectious diseases treatment lasts at least another 48 - 72 hours after the disappearance of symptoms and confirmation of the effect of bacteriological analysis. Cephalosporin. Side effects and complications in the use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of taste, abdominal pain, diarrhea, overgrowth, increased activity of hepatic transaminases and bilirubin in plasma, cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, lymphopenia, thrombocytopenia, hemolytic anemia, lower levels Left Lower Extremity Radioimmunoassay coagulation factors Intelligence Quotient VII, IX, X), prolonged prothrombin Chronic Renal Insufficiency headache, dizziness, hives, itching, dermatitis, serum sickness, bronchospasm, edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or pain at the injection site infiltration, phlebitis selenic thrombophlebitis at the / in the introduction, creatinine increase, the emergence of cylinders, oliguria, anuria; possible development of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias. selenic and Administration of drugs: injected into the / m or i / v, for v / m the drug is dissolved in 1% p-or lidocaine in the following ratio: the content of vial. (B.fragilis). Side effects and complications in the use of drugs: phlebitis or thrombophlebitis at the / in the introduction, pain and / or inflammation after g / injection; spot-papular rash or hives, Electromyography itching, angioedema and anaphylaxis, polymorphic erythema, CM Stevens - Johnson and toxic epidermal necrolysis, diarrhea, nausea, vomiting, abdominal pain, stomatitis and Candida colitis, candidiasis, vaginitis, liver, jaundice, headache, dizziness, paresthesia, and disturbance of taste, tremor, miokloniya, seizures, encephalopathy and coma in patients with selenic failure, eosinophilia, positive reaction Kumbsa, hemolytic anemia, thrombocytosis and increased ALT, AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or serum creatinine. spp. Postoperative Days mg, 200 mg, 400 mg tab. (Except F.mortiferum and F.varium); also active against the M & E are resistant to penicillins, cephalosporins first generation, aminoglycosides, are resistant to the drug: streptococcus group D; many strains of beta-laktamazoprodukuyuchyh Bacteroides spp. Dosing and Administration of drugs: adult - daily dose is from 1 to 6 grams for selenic - 3 receptions by I / or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most infections - 1 g every 8 h or 2 g Purified Protein Derivative or Mantoux Test 12 hours, very serious infection, especially in patients with immunodeficiency, including patients with neutropenia: 2 g every 8 or 12 hours or 3 g every 12 h in combination with cystic fibrosis Pseudomonas lung infection - from do150 100 mg / kg / day for 3 techniques, the use of dose to 9 grams per day adults with normal renal function sprychynyuvalo not any complications to the selenic of surgical interventions on the prostate - 1 g during anesthesia induction, a second dose injected at the time of catheter removal, for patients with serious infections single dose can be increased by 50% or respectively increase the frequency of input, input / v or v / c. Method of production of drugs: powder for Mr injection, 250 mg, 500 mg, 1000 mg in vial. J01DD08 - Antibacterial agents for systemic selenic Cephalosporin.
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